Intrauterine deposition of calcium on copper-bearing intrauterine contraceptive devices

Intrauterine deposition of calcium on copper-bearing intrauterine contraceptive devices

Copper-bearing intrauterine contraceptive devices (IUDs) removed after various times in utero were examined by scanning electron microscopy and xray microanalysis of the elements present. As time in utero increased these devices became increasingly calcified. This calcification may limit the release of copper from the devices and decrease the specific contraceptive effectiveness of copper over an enert plastic device.

Conversely, any teratogenic effects attributable to the copper may decrease with time in utero and depend on the extent of calcification. Even though the amount of copper in the device is not significantly diminished after two years, devices should not remain in situ for over two years because calcium accumulation probably prevents further diffusion of copper.

Calcification can begin as early as six months after insertion.
Consequently a careful review of the amount of time a copper-containing IUD should be left in situ should be undertaken.


This website uses third party cookies

This site uses anonymous technical cookies to ensure navigation and third-party cookies to monitor traffic and to offer additional services such as viewing videos or messaging systems. Without third-party cookies some pages may not work properly. Third-party cookies can track your activity and will only be installed by clicking on the "Accept all cookies" button. You can change your selection at any time by clicking on the "Cookie" link on each page at the bottom left. By clicking on one of the two buttons you declare that you have read the privacy policy and to accept the conditions.
More information